The Blood-Brain Barrier – Volume 1, Number 1
The Blood-Brain Barrier By David Stewart, Ph.D.,R.A.It was thought for years that the interstitial tissues of the brain served as a barrier to keep damaging substances from reaching the neurons of the brain and the cerebrospinal fluid. Instead of a barrier, it would be more accurate to consider it as a sieve or filter through which only molecules of a certain size or smaller can pass.Most of the molecules of the substances used in chemotherapy are too large to pass through the...